LDH活性在人體心臟、肝臟、肌肉、腎臟、肺臟、紅血球等器官組織中可見到。
LDH 若中度以上升高，對於臨床診斷較有價值包括：
①心肌梗塞
http://www.hofferclinic.com/qna_detail.asp?cat=39&deid=287&hfpwd=hf0301ic
②病毒性肝炎
http://www.hofferclinic.com/qna_detail.asp?cat=39&deid=308&hfpwd=hf0301ic
③休克、缺氧及昏迷
http://www.hofferclinic.com/qna_detail.asp?cat=2&deid=1172&hfpwd=hf0301ic
④腎梗塞
http://www.hofferclinic.com/qna_detail.asp?cat=54&deid=1328&hfpwd=hf0301ic
⑤肺梗塞
http://www.hofferclinic.com/qna_detail.asp?cat=32&deid=1455&hfpwd=hf0301ic
⑥傳染性單核球增多症
http://www.hofferclinic.com/qna_detail.asp?cat=39&deid=437&hfpwd=hf0301ic
⑦血癌
http://www.hofferclinic.com/qna_detail.asp?cat=2&deid=1476&hfpwd=hf0301ic
LDH輕度升高：
①肝病
http://www.hofferclinic.com/qna_detail.asp?cat=39&deid=308&hfpwd=hf0301ic
②膽道阻塞／發炎
http://www.hofferclinic.com/qna_detail.asp?cat=32&deid=849&hfpwd=hf0301ic
③甲狀腺低能症
http://www.hofferclinic.com/qna_detail.asp?cat=22&deid=961&hfpwd=hf0301ic
④過度運動
http://www.hofferclinic.com/qna_detail.asp?cat=32&deid=1087&hfpwd=hf0301ic
因此需要與其他指數交叉比對，做較為明確的診斷
LDH 過低，通常意味新陳代謝率或貧血
http://www.hofferclinic.com/qna_detail.asp?cat=39&deid=318&hfpwd=hf0301ic