以上的問題原因，應該探討以下幾個可能性：
1. 自體免疫：類風濕性關節炎(晨僵，好發於晨起時)，或僵直性脊椎炎：
http://www.hofferclinic.com/qna_detail.asp?cat=39&deid=357&hfpwd=hf0501ic
2. 自體免疫：多發硬性化症:
http://www.hofferclinic.com/qna_detail.asp?cat=49&deid=864&hfpwd=hf0501ic
3. 鎂的臨床應用：
http://www.hofferclinic.com/qna_detail.asp?cat=40&deid=325&hfpwd=hf0301ic
4.神經毒素，肌肉緊繃，引起酸痛（毒牙、棘蛋白⋯等)
http://www.hofferclinic.com/qna_detail.asp?cat=32&deid=1441&hfpwd=hf0301ic
5.腳抽筋
http://www.hofferclinic.com/qna_detail.asp?cat=5&deid=751&hfpwd=hf0301ic
6. 胰臟炎/肝/膽發炎：
http://www.hofferclinic.com/qna_detail.asp?cat=32&deid=973&hfpwd=hf0501ic
7．體質（或 婦科下腹疼痛）虛寒，容易腰背肌肉酸痛、抽筋:
http://www.hofferclinic.com/qna_detail.asp?cat=32&deid=469&hfpwd=hf0301ic
http://www.hofferclinic.com/qna_detail.asp?cat=5&deid=751&hfpwd=hf0301ic
8. 脊椎側彎，坐骨神經痛總檢討：
http://www.hofferclinic.com/qna_detail.asp?cat=5&deid=78&hfpwd=hf0501ic